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Inventi Impact: Infectious Diseases & Immunology

Articles

  • Inventi:hidi/22772/17
    Epidemiology and Outcomes in Critically Ill Patients with Human Immunodeficiency Virus Infection\nin the Era of Combination Antiretroviral Therapy
    01-Jan-1970 Research 2017 : July - September
    Shannon L Turvey, Sean M Bagshaw, Dean T Eurich, Wendy I Sligl

    Purpose. The impact of critical illness on survival of HIV-infected patients in the era of antiretroviral therapy remains uncertain.\nWe describe the epidemiology of critical illness in this population and identify predictors of mortality. Materials and Methods.\nRetrospective cohort of HIV-infected patients was admitted to intensive care from 2002 to 2014. Patient sociodemographics,\ncomorbidities, case-mix, illness severity, and 30-daymortalitywere captured.MultivariableCox regression analyseswere performed\nto identify predictors of mortality. Results. Of 282 patients, mean age was 44 years (SD 10) and 169 (59%) were male.Median (IQR)\nCD4 count and plasma viral load (PVL)were 125 cells/mm3 (30ââ?¬â??300) and 28,000 copies/mL (110ââ?¬â??270,000). Fifty-five (20%) patients\ndied within 30 days. Factors independently associated with mortality included APACHE II score (adjusted hazard ratio [aHR] 1.12;\n95% CI 1.08ââ?¬â??1.16;

    How to Cite this Article
    CC Compliant Citation: Shannon L. Turvey, Sean M. Bagshaw, Dean\nT. Eurich, and Wendy I. Sligl, â??Epidemiology and Outcomes in\nCritically Ill Patients with Human Immunodeficiency Virus\nInfection in the Era of Combination Antiretroviral Therapy,â?\nCanadian Journal of Infectious Diseases and Medical Microbiology,\nvol. 2017, Article ID 7868954, 9 pages, 2017.\ndoi:10.1155/2017/7868954, http://creativecommons.org/\nlicenses/by/4.0/.
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